Antibodies to β2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus
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چکیده
منابع مشابه
Prevalence of Anti-Cardiolipin and Anti-β2 Glycoprotein Antibodies in Indian Systemic Lupus Erythematosus Patients
Anti-phospholipid antibodies (APA) like anti-cardiolipin antibodies (ACA) and anti-β2glycoprotien (anti-β2 GP) are important cause of venous and arterial thrombosis and other occlusive vascular diseases. The prevalence of these antibodies in SLE patients at the time of diagnosis is not known in Indian SLE patients. This study was conducted to evaluate the prevalence of ACA and anti-β2 GP autoan...
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Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...
متن کاملAnticardiolipin Antibodies in Juvenile Rheumatoid Arthritis and Systemic Lupus Erythematosus
Background: Antiphospholipid antibody syndrome (APS) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Anticardiolipin antibody (aCL) of IgG and/or IgM isotype in blood, measured by a standardized ELISA is the most acceptable laboratory criteria. APS IgG isotype, particularly IgG2 subclass is more strongly associated ...
متن کاملCutaneous Manifestations of Systemic Lupus Erythematosus in Iranian Children
Systemic lupus erythematous (SLE) is an autoimmune process in which cutaneous lesions occur in majority of patients. This study was conducted to determine the pattern and prevalence of such lesions in SLE in Iranian children infected with SLE. Forty-eight patients, age between 3-16 yrs and male to female ratio of 7/1 were examined for the presence of cutaneous manifestations of SLE. The most co...
متن کاملIgG anti-beta2-glycoprotein I antibodies in adult patients with systemic lupus erythematosus.
OBJECTIVE To investigate the prevalence of serum anti-beta2-glycoprotein I (anti-beta2-GPI) antibodies and other antiphospholipid antibodies (aPL) in patients with systemic lupus erythematosus (SLE). To study their diagnostic value for the antiphospholipid syndrome (APS). METHODS Anti-beta2-GPI and IgG anticardiolipin (aCL) were determined in sera from 102 consecutive patients with SLE using ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1996
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780390905